CNN —

American Frances Tiafoe’s hopes of reaching his first semifinal at Roland Garros came to an end against Italy’s Lorenzo Musetti on Tuesday.

Musetti triumphed 6-2, 4-6, 7-5, 6-2 on Court Philippe-Chatrier to reach the final four of a grand slam for the second time in his career, having also done so at last year’s Wimbledon.

The 23-year-old will now face either defending champion Carlos Alcaraz or American 12-seed Tommy Paul in Friday’s semifinals.

Both Tiafoe and Musetti were enjoying their best-ever runs at the French Open heading into their quarterfinal, and it was the latter who took an early advantage by breaking Tiafoe twice and wrapping up the opening set in 37 minutes.

The world No. 16 responded with a break in the third game of the second set before going on to leve

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