The top federal prosecutor for the Eastern District of Missouri has resigned.

U.S. Attorney Sayler A. Fleming leaves the St. Louis-based office after heading it for four and a half years. She was appointed in late 2020 during the first administration of President Donald Trump.

Fleming couldn't immediately be reached for comment Tuesday about why she resigned.

“It has been the privilege of a lifetime to lead the United States Attorney’s Office for the last four and a half years,” Fleming said in a statement released Tuesday . “As a federal prosecutor in the Eastern District of Missouri, I have had the great fortune of working with some of the most dedicated law enforcement professionals in the country, and I am extremely grateful for the sacrifices they make every day for our safety.”

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