Wrist-based accelerometry feasible for continuous monitoring in motor neuron disease

Key takeaways:

Accelerometers showed a slower rate of decline vs. ALSFRS-R scores, with strong correlation in motor domains.

Longitudinal analysis deemed accelerometer data complementary to ALSFRS-R, indicating viability.

Wrist-based accelerometry may be a feasible method for continuous monitoring for individuals with motor neuron disease, according to data published in eBioMedicine .

“Actigraphy, which leverages wearable sensors to monitor movement, provides a promising platform for identifying novel outcome measures outside the clinic,” Cory J. Holdom, a doctoral student at the Australian Institute for Bioengineering and Nanotechnology at the University of Queensland, and colleagues wrote.

Data were derived from Holdom CJ, et al. EBioMedicine . 2025;doi:10.1016/j.ebiom.2025.