A monthly treatment from Otsuka reduced by more than half the levels of a toxic protein in the urine of patients with an autoimmune kidney disease. The results presented Friday achieved the interim goal of a Phase 3 study and were numerically superior to study results posted Monday by a competitor, Vera Therapeutics.

The Otsuka drug, called sibeprenlimab, lowered proteinuria levels by 50.2% after nine months compared to an increase of 2.1% in patients given a placebo. The statistically significant difference was 51.2%.

Serious side effects were reported by 3.9% of patients on sibeprenlimab comapred to 5.4% of patients treated with placebo.

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