The Buffalo Bills are in the process of trimming their roster to 53 players ahead of the NFL deadline. Teams must be at or under 53 players by 4 p.m. EDT on Tuesday, August 26, 2025.

But that doesn’t mean the roster shuffling is over. Every team’s practice squad has become essential for flexibility to develop talent, manage injuries, and prepare for the long grind of the season.

The rules and regulations governing the practice squad have evolved over time, and as we head into the 2025 NFL season, it’s crucial to understand how teams are leveraging this component of their rosters. There were no major NFL practice squad rule changes announced for the 2025 season, with the current rules remaining largely in place.

So with that in mind, here’s a reminder of the rules, salary details, and ho

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