Grimsby's reward for toppling Manchester United in the Carabao Cup is a third-round trip to crisis club Sheffield Wednesday.
The League Two Mariners pulled off one of the biggest shocks in the competition's history by beating the Premier League giants following a mammoth penalty shootout and will now travel to Hillsborough with a realistic shot of making the fourth round.
Liverpool will host Southampton and there is also a home tie for defending champions Newcastle as they welcome League One Bradford.
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Arsenal , Chelsea , Tottenham and Manchester City will all also face third-tier opposition.
The Gunners visit Port Vale, Enzo Maresca's side head to Lincoln ,