The Diageo plant in Amherstburg, Ont., is set to close in February as part of what the company called an effort to "increase efficiency."
The facility is one of the Canadian plants that bottles Crown Royal whisky.
The company said the whisky will continue to be mashed, distilled and aged in Canada, but the move was an effort to shift "some bottling volume to be closer to its many U.S. Crown Royal consumers."
"Diageo will maintain its significant footprint across Canada, including at our Canadian headquarters and warehouse operations in the Greater Toronto Area and other bottling and distillation facilities in Gimli, Manitoba and Valleyfield, Quebec," the statement read.
'Shocking and devastating'
The union representing workers at the plant said it won't let the facility close without