The implosion of leadership at the Centers for Disease Control and Prevention threatens the agency, its mission, and the trust people place in public health, medical experts told STAT Thursday, a day after Director Susan Monarez refused to dismiss top scientists only to be ousted herself.

The crisis in the agency, which has been battered by personnel and policy changes ordered by health secretary Robert F. Kennedy Jr., is spilling into real-world harms, the experts said. They are seeing uncertainty from the public about vaccine recommendations and availability, in light of new Covid-19 vaccine policies announced by Kennedy, as well as deeper concerns about emergency preparedness for the inevitable next challenge to the nation’s health.

“I’m worried that CDC will not be there with t

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