Week 1 of the 2025 college football season officially began Thursday night, and we have another loaded weeknight slate of games on Friday as we prepare for the first Saturday of the season.

Among the headlining games on Friday is an intriguing Big 12 vs. ACC matchup as Colorado hosts Georgia Tech. The Buffaloes enter a new era without Shedeur Sanders or Travis Hunter, while the Yellow Jackets look to build off a promising 2024 campaign.

If you're looking to get back in the swing of football season and need some betting advice for Friday's matchup in Boulder, we've got you covered. Here are the latest odds for the game, courtesy of BetMGM.

Stream Colorado vs. Georgia Tech

Colorado vs. Georgia Tech game odds:

All college football odds via BetMGM

  • Spread: Georgia Tech -4.5 (-105), Colorado +4.5 (-115)
  • Money Line: Georgia Tech -190, Colorado +155
  • Over-Under: Over 51.5 (-118), Under 51.5 (-102)

Colorado vs. Georgia Tech prediction, pick:

Even with a promising addition in quarterback Kaidon Salter, it's hard to see the Buffaloes not taking at least a bit of a step back this season. Georgia Tech, meanwhile, managed to keep much of its core including quarterback Haynes King and running back Justice Haynes. Colorado has the benefit of playing at home, but I just trust the Yellow Jackets a bit more.

Prediction: Georgia Tech 27, Colorado 21

Best Bet: GT -4.5, Under 51.5

Colorado vs. Georgia Tech channel, start time, streaming:

Time: 8 p.m. ET

TV Channel: ESPN

Live Stream: ESPN App

Get more betting analysis and predictions at Sportsbook Wire.

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This article originally appeared on College Sports Wire: Colorado vs. Georgia Tech: Week 1 College Football Betting Odds, Prediction, Pick

Reporting by Tyler Nettuno, College Sports Wire / College Sports Wire

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