The Virginia Tech Hokies take on the 13th-ranked South Carolina Gamecocks in a 2025 Aflac Kickoff Game season-opening battle on Sunday. It will be the first meeting between the teams since 1991. The Hokies (6-7 in 2024), who tied for eighth in the Atlantic Coast Conference at 4-4 last season, were 0-1 at a neutral site. The Gamecocks (9-4 in 2024), who tied for fourth in the Southeastern Conference at 5-3 a year ago, were 0-1 at a neutral site.

Kickoff is set for 3 p.m. ET at Mercedes-Benz Stadium in Atlanta. South Carolina leads the all-time series 11-7-2, but Virginia Tech holds a 3-1 edge at neutral sites. The Gamecocks are 7-point favorites in the latest Virginia Tech vs. South Carolina odds, while the over/under for total points scored is 51.5, up three points from the opening li

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