The Gates Foundation — the homegrown philanthropic force that has funneled billions into the region and across the world since its founding 25 years ago — will sunset in 2045, Bill Gates announced Thursday.

Gates said he will give away nearly all his remaining tech fortune, about $107 billion, as his foundation accelerates donations in global health efforts. The foundation expects to ultimately disburse more than $200 billion between today and its eventual closure, double its giving over the past quarter-century.

“It’s kind of thrilling to have that much to be able to put into these causes,” Gates said in an interview with The Associated Press.

Gates, who was born in Seattle and co-founded Microsoft 50 years ago, launched the foundation with his then-wife Melinda French Gates in 2000 wh

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