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More than 100 firefighters are battling a massive blaze that caused multiple high-rise buildings to ignite in Baltimore’s city center Tuesday afternoon.

Baltimore City Fire Department (BCFD) officials confirmed the five-alarm fire is downtown near North Howard and West Fayette streets. As of 4:40 p.m., crews continued to attempt to contain the fire.

One building collapsed, and two four-story buildings ignited, according to officials. All three buildings are presumed to have been vacant, though crews have not entered because the structures are unstable.

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“At this time, BCFD crews are making an exterior attack with ladder pipes and large

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