The 11th-ranked Illinois Fighting Illini will look to stay unbeaten when they battle the Duke Blue Devils in a Week 2 college football matchup on Saturday. Illinois is coming off a 52-3 season-opening win over Western Illinois, while Duke defeated Elon 45-17. The Fighting Illini, who finished 10-3 a year ago, were 2-2 on the road. The Blue Devils, who were 9-4 in 2024, were 5-1 on their home field.

Kickoff from Brooks Field at Wallace Wade Stadium in Durham, N.C., is set for noon ET. The all-time series is tied 1-1. The Fighting Illini are 2.5-point favorites in the latest Illinois vs. Duke odds from SportsLine consensus, while the over/under for total points scored is 49.5. Before making any Duke vs. Illinois picks, make sure you check out what SportsLine expert, Emory Hunt, has to

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