ENGLEWOOD, Colo. (AP) — The Denver Broncos have ruled out two key defensive players for their opener against the Tennessee Titans on Sunday: inside linebacker Dre Greenlaw and defensive tackle Malcolm Roach.

Greenlaw has been bothered by a left quadriceps injury all offseason. After pulling up lame in a one-on-one drill July 31, he was held out of the Broncos’ three preseason games and both of their joint practices in training camp.

He missed practice this week, working on a side field instead.

Coach Sean Payton declined to discuss the injuries on Friday. Earlier this week, Payton said the Broncos were taking a conservative approach to Greenlaw’s workload: “It’s a long season, so most importantly, having him not only healthy early on but for the long haul is the goal.”

Greenlaw, who si

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