Illinois football returns to the field as slight road favorites against Duke at 11 a.m. Saturday at Wade Wallace Stadium in Durham, North Carolina.

Coach Bret Bielema and the No. 12 Illini are coming off a 52-3 win over Western Illinois and is picked to finish fifth in the Big Ten Conference by the USA TODAY Network. Duke, which defeated Elon 45-17 last week, is picked sixth in the ACC.

Here are the betting odds and a few predictions heading into the game: Stream Illinois vs. Duke on Fubo (free trial available)

Illinois vs. Duke odds , money line, over/under

Odds courtesy of BetMGM as of Thursday, Sept. 4 . Expert MLB daily picks: Unique MLB betting insights only at USA TODAY

Moneyline: Illinois -158, Duke +133

Spread: Illinois by 3

Over/under: 49.5 points

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