Seven New Orleans Saints players were listed on Wednesday's Injury Report for the team's Week 2 game against the San Francisco 49ers during the 2025 NFL season. Additionally, the Saints announced that the team signed DE Fadil Diggs to the practice squad and terminated the practice squad contract of QB Hunter Dekkers.

NEW ORLEANS SAINTS Position Name Injury Wednesday S Julian Blackmon Shoulder DNP T Taliese Fuaga Knee DNP T/G Trevor Penning Toe DNP DE Chase Young Calf DNP LS Zach Wood Elbow LP RB Velus Jones Jr. Knee LP DB Jordan Howden Oblique FP

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