Injuries are already biting the San Francisco 49ers after two of their top players were dinged up last week in the season-opening win over the Seattle Seahawks, yet the Niners are still 3-point favorites in Week 2. Quarterback Brock Purdy (toe, shoulder) is a longshot to play, per coach Kyle Shanahan, while tight end George Kittle (hamstring) will miss at least four weeks. With some NFL survivor pools already starting to thin down, its time to lock in Week 2 NFL survivor picks if you haven't already.

The latest Week 2 NFL odds show six games with a spread of 5 points or more, including Browns vs. Ravens (-11.5), Giants vs. Cowboys (-5.5), Bills vs. Jets (+6.5), Rams vs. Titans (+5.5), Panthers vs. Cardinals (-6.5) and Falcons vs. Vikings (-4.5). Those are the games many NFL survivor playe

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