Michigan State (3-0) at No. 25 USC (3-0), Sept. 20 at 11 p.m. EDT.

BetMGM College Football Odds Opening Line: USC by 18.5. Against the spread: USC 2-1, Michigan State 0-3.

How to watch: FOX

Key stats

USC Offense

Overall: 604 yards per game (1st in FBS)

Passing: 364 yards per game (6th)

Rushing: 240 yards per game (17th)

Scoring: 55 points per game (2nd)

USC Defense

Overall: 319.3 yards per game (59th in FBS)

Passing: 233 yards per game (98th)

Rushing: 86.3 yards per game (22nd)

Scoring: 16.7 points per game (41st)

Michigan State Offense

Overall: 386.7 yards per game (72nd in FBS)

Passing: 218.7 yards per game (76th)

Rushing: 168 yards per game (67th)

Scoring: 35.3 points per game (51st)

Michigan State Defense

Overall: 337.7 yards per game (73rd in FBS)

Passing: 273.3

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