Road favorites have covered at at 64% clip thus far in the 2025 NFL season, and there are several teams favored in away games to utilize in Week 3 NFL picks. That includes the Packers (-8.5) versus the Browns, as not only is this one of the largest Week 3 NFL spreads, but it makes Green Bay the biggest road favorite of the entire season. Other teams giving points in away stadiums on Sunday afternoon include the Falcons (-5.5) against the Panthers, the Steelers (-1.5) versus the Patriots, and the Colts (-4.5) against the Titans.

Then on Sunday night, and in the only matchup on the Week 3 NFL schedule of winless teams, the Chiefs are 6-point road favorites at the Giants. While away favorites have won against the spread 64% of the time, road favorites have outright prevailed in 79% of games

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