Seattle Children’s Hospital has announced a round of layoffs Wednesday that will affect 154 employees at five of its Washington hospitals, according to a state filing with the Employment Security Department.

The layoffs will take effect on Nov. 15, cutting down on staff across locations in Seattle, Bellevue, Everett, Federal Way, and Kennewick.

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Seattle Children’s will also eliminate 350 of its open positions, a move that the company claimed was caused by federal funding losses.

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