LA Dodgers first baseman Freddie Freeman (5) gestures after hitting a double against the San Francisco Giants during an MLB game at Oracle Park in San Francisco, California.

The San Francisco Giants (76-76) and the Los Angeles Dodgers (85-67) open a 4-game series Thursday at Dodger Stadium in Los Angeles. First pitch is scheduled for 10:10 p.m. ET (MLB Network). Let's analyze BetMGM Sportsbook's MLB odds around the Giants vs. Dodgers odds and make our expert MLB picks and predictions for the best bets.

Season series: Dodgers lead 6-3

The Giants picked up a 5-1 win in 11 innings in the series finale against the Arizona Diamondbacks Wednesday, avoiding a sweep thanks to the red-hot RHP Justin Verlander. He allowed just 3 hits and 2 walks with 3 strikeouts across 7 scoreless innings in the no-decision. Meanwhile, 2B Christian Koss came up with a big 2-run double in the 11th.

The Dodgers also avoided a sweep Wednesday with a 5-0 win over the Philadelphia Phillies, after dropping the first 2 games by a combined 15-11 score. LHP Blake Snell threw 7 scoreless innings, while striking out 12. Offensively, 5 different Dodgers had an RBI, including solo homers by DH Shohei Ohtani and 1B Freddie Freeman.

LA is a subpar 8-10 across the past 18 games, but it did take 2 of 3 games in San Francisco last weekend, outscoring the Giants 24-14 as the Over hit twice.

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Giants at Dodgers projected starters

RHP Logan Webb vs. RHP Yoshinobu Yamamoto

Webb (14-10, 3.34 ERA) makes his 32nd start. He has a 1.26 WHIP, 2.1 BB/9 and 9.8 K/9 through 188 2/3 innings.

  • Last start: Loss, 4 IP, 6 ER, 10 H (1 HR), 2 BB, 5 K in 13-7 home loss vs. Dodgers Saturday
  • Last 7 starts: 4-2, 3.70 ERA (41 1/3 IP, 17 ER), 9 BB, 41 K, 1.31 WHIP
  • 2025 road stats: 7-6, 3.54 ERA (84 IP, 33 ER), 5 HR, 22 BB, 93 K, 1.30 WHIP
  • Career vs. Dodgers (regular season): 6-7, 4.69 ERA (101 2/3 IP, 53 ER), 11 HR, 35 BB, 86 K, 1.38 WHIP, 7.6 K/9 in 19 starts

Yamamoto (11-8, 2.66 ERA) makes his 31st start. He has a 0.98 WHIP, 2.8 BB/9 and 10.4 K/9 through 162 1/3 innings.

  • Last start: No-decision, 7 IP, 1 ER, 1 H, 1 BB, 10 K in 5-1 loss in 10 innings vs. Giants last Friday
  • Last 7 starts: 2-1, 2.74 ERA (46 IP, 14 ER), 12 BB, 54 K, 0.80 WHIP
  • 2025 home stats: 3-4, 3.30 ERA (62 2/3 IP, 23 ER), 7 HR, 21 BB, 76 K, 1.13 WHIP in 11 starts
  • Career vs. Giants: 0-1, 3.70 ERA (24 1/3 IP, 10 ER), 3 HR, 10 BB, 27 K, 1.03 WHIP, 10.0 K/9 in 4 starts

Giants at Dodgers odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 6:43 p.m. ET.

  • Moneyline (ML): Giants +145 (bet $100 to win $145) | Dodgers -175 (bet $175 to win $100)
  • Run line (RL)/Against the spread (ATS): Giants +1.5 (-155) | Dodgers -1.5 (+130)
  • Over/Under (O/U): 7.5 (O: -115 | U: -105)

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Giants at Dodgers picks and predictions

Prediction

Dodgers 5, Giants 3

Moneyline

The DODGERS (-175) are a little on the expensive side, and betting it straight up is less attractive than tossing LA into a multi-leg parlay. You can also use a boost or promo to drop the price down a bit.

The Dodgers should be able to take care of the Giants, but there is risk here. First off, Yamamoto is winless in 4 career starts against San Francisco. Plus, the Dodgers have a losing record since late August, so tread lightly.

Run line/Against the spread

If you're really adventurous, DODGERS -1.5 (+130) are worth a look behind Yamamoto at home. He has solid splits, and while he is winless in 4 career tries against the Giants, he baffled then in San Francisco over the weekend in a no-decision. And, be careful, the Under is 3-1-1 in the past 5 starts by Yamamoto.

Over/Under

OVER 7.5 (-115) is the lean, but go with a half-unit play at most.

The Over is 4-1 in the past 5 games for the Dodgers, although the Under cash in the most recent game Wednesday.

The Giants have seen the Over hold a 3-2 edge in the past 5 games, while going cashing in 3 straight starts by Webb, while going 5-1 in his past 6 outings.

For more sports betting picks and tips, check out SportsbookWire.com and BetFTW.

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This article originally appeared on Sportsbook Wire: San Francisco Giants at LA Dodgers odds, picks and predictions

Reporting by Daniel Dobish, Sportsbook Wire / Sportsbook Wire

USA TODAY Network via Reuters Connect