Duke football is back at Wallace Wade Stadium to host NC State and open ACC play on Saturday, Sept. 20 (4 p.m. ET, ESPN2).

The Blue Devils (1-2) will look to get back in the win column after dropping back-to-back contests against Illinois and on the road at Tulane. They face a 3-0 NC State team coming off a 34-24 Week 3 win over Wake Forest to open ACC play.

Duke will be looking for its third-straight win over NC State, owning a 43-37-5 series record against the Wolfpack and going 25-16-1 when playing them at home. NC State will be looking first its win in Durham since 2008 and its first win over Duke since 2020.

Here are picks, predictions and odds for Duke's Week 4 matchup with NC State. Stream Duke vs. NC State on FUBO (free trial)

Duke vs NC State odds, money line, over/und

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