Big Ten teams are set to square off in a primetime matchup on Friday when the Rutgers Scarlet Knights host the Iowa Hawkeyes. The Hawkeyes (2-1) are aiming to build off their 47-7 win over UMass in Week 3. Iowa has been dominant on the defensive side of the ball in 2025, allowing only 27 points in three games. The Scarlet Knights (3-0) are also coming off a blowout win in Week 3 after beating Norfolk State 60-10. Rutgers quarterback Athan Kaliakmanis has played at a high level thus far in 2025. The Hawkeyes are 1-1-1 and the Scarlet Knights are 2-1 against the spread this season.
Kickoff from SHI Stadium in Piscataway, N.J., is set for 8 p.m. ET. The Hawkeyes are 2.5-point favorites in the latest Iowa vs. Rutgers odds, while the over/under for total points scored is 45.5. Before making an