Conference battles heat up during the Week 4 college football schedule. One of the headliners is Illinois vs. Indiana (-6.5), while Michigan vs. Nebraska (+2.5) and USC vs. Michigan State (+18.5) also unfold in the Big Ten. Utah vs. Texas Tech (+3.5) is the top Big 12 matchup, while the SEC features Oklahoma vs. Auburn (+7) and South Carolina vs. Missouri (-9.5).
There are some intriguing non-conference games between in-state rivals as well as Notre Dame vs. Purdue (+24.5), Oregon vs. Oregon State (+35.5), Florida vs. Miami (+9.5) and Washington vs. Washington State (+19.5) also on the slate. Which Week 4 college football odds bring the most value? Before locking in any Week 4 college football picks on those game or others, be sure to see the top Week 4 college football expert picks, pre