A new study published in the journal of BMC Nephrology showed that as a non-invasive biomarker to distinguish between steroid-resistant nephrotic syndrome (SRNS) and steroid-sensitive nephrotic syndrome (SSNS), urinary neutrophil gelatinase-associated lipocalin (NGAL) has great promise for supporting early diagnosis, risk assessment, and treatment.
Massive proteinuria (more than 40 mg/m^2 per hour) causes hypoalbuminemia (less than 30 g/L), which leads to hyperlipidemia, edema, and other problems. Nephrotic syndrome is a clinical illness characterized by this condition. Although patient response varies, corticosteroids are usually used as the first line of treatment.
Early in the course of the disease, it's critical to distinguish between steroid-sensitive nephrotic syndrome (SSNS) and