Welcome to Week 5!

Louisville football , still undefeated, has its first road test of the season at Pitt this Saturday. Kentucky is back in action after an early bye and headed to Columbia, South Carolina , looking to break some unfortunate streaks with a conference dub.

Those two games are part of The Courier Journal's picks slate, as are Western Kentucky vs. Missouri State , No. 4 LSU vs. No. 11 Ole Miss and No. 5 Oregon vs. No. 2 Penn State .

Here's a look at this week's picks. As is our custom, predictions are straight-up winners and losers (not against the spread), with rankings based on the latest US LBM Coaches Poll . All times listed are ET, and all odds listed are per DraftKings as of Tuesday.

Louisville at Pitt

How to watch : noon Saturday, ESPN2

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