SANTA CLARA, Calif. (AP) — The San Francisco 49ers have dealt with a string of injuries early this season that have forced them to play without stars such as George Kittle and Brock Purdy.

They have overcome that to get off to a 3-0 start , but now face an even bigger test with star defensive end Nick Bosa out for the season after tearing the ACL in his right knee on Sunday.

“I’m sick,” linebacker Fred Warner said. “I’m so sick for him because he knows what that’s like to go through that process of recovery from that injury, which I know he’s fully capable of but that doesn’t make it any easier. Obviously it’s a huge blow to our team, but we move forward. I hate to say next man up mentality because you can’t just replace him with one player. But the mission is still the same.”

This

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