Week 4 of the 2025 NFL season begins with an NFC West showdown between the Seattle Seahawks and Arizona Cardinals.

Both teams come in with 2-1 records in what looks like a loaded division. Both teams' only loss came to NFC West leaders San Francisco in one score games.

Seattle is a slight road favorite in what is supposed to be one of the most competitive games of the week.

What time is Thursday Night Football?

The game featuring the Seattle Seahawks at the Arizona Cardinals starts at 6:15 p.m. CT/7:15 p.m. MT from State Farm Stadium in Glendale.

What channel is Thursday Night Football on?

The game will stream on Amazon Prime.

Streaming: Amazon Prime

Seahawks at Cardinals odds

Seattle -1 1/2. Over-under 43 1/2. Seattle is -125 on the money line, Arizona is +105.

Seahawks

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