Updated: September 25 at 3:00 p.m.

The Jacksonville Jaguars are headed to the West Coast to take on the San Francisco 49ers in Week 4 of the 2025 NFL Season.

This road matchup kicks off at 4:05 p.m. ET from Levi's Stadium.

Follow along here for live updates, behind-the-scenes content, and full coverage throughout the game. ⬇️

Top Content: Jaguars vs. 49ers | Week Four

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