Week 3 was an absolute rollercoaster ride. Can we expect more of that in Week 4? Well, we’ll start to get an idea on Thursday night, when the Seattle Seahawks and Arizona Cardinals do battle in an NFC West showdown. So, let’s dig into the ClutchPoints 2025 NFL Week 4 picks, predictions, and odds column.

Things were progressing nicely from a betting perspective in Week 3, right up until about 3:30 p.m. ET on Sunday. That’s when all hell broke loose. Picks were sixed, field goals blocked, and, to paraphrase the Red Zone’s Chris Hanson, wins became losses, and losses… well, they pretty much stayed losses.

But that’s OK. It’s the life of an NFL bettor, and we dust ourselves off, learn from our mistakes, and move on to the NFL Week 4 slate.

Here in Week 4, the schedule gets a little funky

See Full Page