Domestic equity benchmarks suffered sharp losses on Friday amid a broad-based sell-off after US President Donald Trump announced a 100 per cent tariff on branded and patented drugs that battered pharma stocks while IT shares weakened following Accenture's quarterly earnings pointed to muted demand for technology. The Trump 2.0 also announced other tariff actions, fuelling fresh concerns about the impact of US levies on global trade. Both headline indices fell 0.9 per cent for the day. The Sensex gave up 733.2 points to end at 80,426.5 while the Nifty50 gave up 220.2 points to 24,670.7.

Top Nifty50 losers and gainers

IndusInd Bank, Mahindra & Mahindra, Tata Steel, Eternal, Bajaj Finance, Sun Pharma, Asian Paints, Tech Mahindra, Wipro and Infosys -- closing between 2.2 per cent and 3.

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