The gunman who killed four people during a mass shooting at a Midtown office building in July suffered from chronic traumatic encephalopathy, or CTE, the city’s medical examiner said Friday.

The Office of Chief Medical Examiner said it found “unambiguous diagnostic evidence” of the trauma-induced neurodegenerative disease in the brain tissue of Shane Tamura, 27, of Las Vegas. Tamura died by suicide after opening fire inside 345 Park Ave., which houses the NFL’s headquarters, on July 28.

“The findings correspond with the classification of low-stage CTE, according to current consensus criteria,” the office said in a statement.

The conclusion supports claims Tamura made in a suicide note, where he wrote that he believed he suffered from the brain injury often linked to contact sports.

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