The Missouri Lottery offers several draw games for those aiming to win big. Here’s a look at Sept. 27, 2025, results for each game:

Winning Powerball numbers from Sept. 27 drawing

10-16-32-61-66, Powerball: 04, Power Play: 2

Check Powerball payouts and previous drawings here.

Winning Pick 3 numbers from Sept. 27 drawing

Midday: 3-1-9

Midday Wild: 6

Evening: 1-7-9

Evening Wild: 9

Check Pick 3 payouts and previous drawings here.

Winning Pick 4 numbers from Sept. 27 drawing

Midday: 0-1-1-9

Midday Wild: 9

Evening: 8-1-3-6

Evening Wild: 1

Check Pick 4 payouts and previous drawings here.

Winning Cash4Life numbers from Sept. 27 drawing

08-15-28-49-51, Cash Ball: 03

Check Cash4Life payouts and previous drawings here.

Winning Cash Pop numbers from Sept. 27 drawing

Early Bird:

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