AI-assisted summary

The New Orleans Saints will face the Buffalo Bills in Week 4 of the 2025 NFL season.

Kickoff is scheduled for 1 p.m. ET on Sunday, September 28, 2025, at Highmark Stadium.

The game will be broadcast on CBS and can be streamed on NFL+.

Entering the matchup, the Buffalo Bills are undefeated at 3-0, while the New Orleans Saints are winless at 0-3.

Week 4 of the 2025 NFL season continues with the New Orleans Saints traveling to Highmark Stadium to take on the Buffalo Bills on Sunday.

Here's what you need to know about how to watch the Bills vs. the Saints , today's matchup , the NFL Week 4 schedule , TV lineup and more. 2025 NFL season record AI predictions: Win-loss picks for all 32 teams

What time does Buffalo Bills - New Orleans Saints ga

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