Key Takeaways

An invisible storm brews in the bodies of people developing rheumatoid arthritisThey experience widespread systemic inflammation before any joint pain developsThese patients also experience specific changes in immune cells and inflammatory cells

MONDAY, Sept. 29, 2025 (HealthDay News) — An invisible storm might rage for years inside the bodies of people at risk for rheumatoid arthritis , prior to any joint pain occurring, a new study says.

These folks experience dramatic immune system changes long before they feel symptoms, researchers reported in the journal Science Translational Medicine .

“Overall, we hope this study raises awareness that rheumatoid arthritis begins much earlier than previously thought and that it enables researchers to make data-driven decisions o

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