San Francisco (3-1) at Los Angeles Rams (3-1)

Thursday, 8:15 p.m. EDT, Prime Video

BetMGM NFL Odds: Rams by 7

Against the spread: 49ers 2-2; Rams 3-1

Series record: 49ers lead 78-71-3.

Last meeting: Rams beat 49ers 12-6 in Santa Clara, California on Dec. 12, 2024.

Last week: 49ers lost to Jaguars 26-21; Rams beat Colts 27-20.

49ers offense: overall (5), rush (28), pass (2), scoring (23).

49ers defense: overall (T-5), rush (17), pass (6), scoring (7).

Rams offense: overall (4), rush (13), pass (3), scoring (13).

Rams defense: overall (9), rush (10), pass (T-9), scoring (T-10).

Turnover differential: 49ers minus-5; Rams plus-3.

49ers player to watch

RB Christian McCaffrey. McCaffrey had 92 yards receiving last week for his most since joining the Niners. He is one of four players

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