SANTA CLARA, Calif. (AP) — Quarterback Brock Purdy will miss his third game of the season for the San Francisco 49ers because of an injury to his toe.

Purdy missed games in Week 2 and 3 with the injured toe before returning this past Sunday against Jacksonville. He came out of that game with more soreness and will be unable to play Thursday night on a short week against the Los Angeles Rams .

Mac Jones will start in Purdy’s place. Jones won both starts in Purdy’s absence earlier this season, throwing for 563 yards with four TDs and one interception in wins over New Orleans and Arizona .

The Niners (3-1) also ruled out starting receivers Ricky Pearsall and Jauan Jennings for the division showdown, with Pearsall out because of a knee injury and Jennings with injuries to his ankle

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