There are several interesting quarterback matchups on Sunday that could add some spice to your Week 5 NFL picks. QBs who've had more success since leaving New York, in Geno Smith and Daniel Jones, meet in Raiders vs. Colts (-6.5). A pair of former Alabama signal callers in Tua Tagovailoa and Bryce Young square off in Dolphins vs. Panthers (+1.5), while No. 1 picks in Cam Ward and Kyler Murray meet in Titans vs. Cardinals (-7.5). Not only can you target these games with Week 5 NFL bets, but the respective QBs can be used as NFL DFS picks, in Week 5 Fantasy football lineups, or in NFL player props.

A Week 5 NFL betting guide would help identify the NFL lines to target with your picks, either for these matchups or others. Nine games have a spread of 3.5 points or fewer, per the latest Week 5

See Full Page