Should I start Kendrick Bourne, Demarcus Robinson, Jake Tonges for Week 5? Fantasy football start 'em, sit 'em picks and recommendations for the 2025 NFL season.

The San Francisco 49ers are currently dealing with many injuries to key offensive players. For their Week 5 matchup against the Los Angeles Rams, on Thursday evening, they will be without starting QB Brock Purdy , top wide receivers Jauan Jennings and Ricky Pearsall , and starting tight end George Kittle .

As a result, many players who served in depth roles are set to play a key role on Thursday evening and carry sneaky fantasy value.

So, should fantasy managers start Bourne, Robinson, and Tonges in Week 5? Let's dive in and find out. Be sure to check all of our fantasy football rankings for 2025:

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