Four people were injured and a suspected knifeman shot by police Thursday after a car ramming and stabbing incident outside a synagogue in Manchester, officials said.

Greater Manchester Police declared a "major incident" shortly after 9:30am (0830 GMT) after officers were called to the Heaton Park Hebrew Congregation Synagogue in the Crumpsall neighbourhood of the northwestern city.

"Paramedics arrived at the scene...and are tending to members of the public," it added, noting "currently four members of the public with injuries caused by both the vehicle and stab wounds."

"Shots were fired by Greater Manchester Police firearms officers at 9:38am. One man has been shot, believed to be the offender," the force said in a statement.

The incident came on the Jewish Yom Kippur holiday and day

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