The good news for the 49ers is that running back Christian McCaffrey is in the lineup for their “Thursday Night Football” game against the Rams. The bad news is that just about every other key San Francisco starter is out.

The lengthy 49ers injury report is why Los Angeles has shot up from a 3-point home favorite to as high as a 9-point favorite.

Starting quarterback Brock Purdy and wide receivers Ricky Pearsall and Jauan Jennings have been ruled out with injuries for a San Francisco team that was already missing tight end George Kittle, wide receiver Brandon Aiyuk and edge rusher Nick Bosa.

“The whole team is banged up,” Westgate SuperBook vice president of risk Ed Salmons said. “They’re just a MASH unit right now.”

The 49ers won and covered their first three games over the Seahawks,

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