When will Joe Mixon return and play? Will Joe Mixon be back again this season? Read the latest Joe Mixon injury updates and return date for Week 5 (2025).

Houston Texans running back Joe Mixon (foot) has been on the non-football injury/reserve list since the beginning of the season. The team has not provided any significant updates on its status, leaving managers in a difficult position.

While he is eligible to return in Week 5, seeing that he has yet to practice suggests he is still facing a lengthy recovery timeline.

When will Joe Mixon return to action, and what is his fantasy football outlook when he does? Let's dive in. Be sure to check all of our fantasy football rankings for 2025:

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