NFL.com analysts provide one bold prediction for Week 5 of the 2025 NFL season , from fantasy forecasts to team-based takes.

Matt Okada Programmer, Fantasy Content

         Drake Maye          leads the Patriots to a prime-time upset of the Bills.

The NFL’s current leader in completion rate -- Maye's at a pristine 74 percent through four games -- faces a tough test in the division-rival Bills on Sunday night. Not only will he pass the test -- the second-year pro will complete 30+ passes for 300+ yards and 3+ touchdowns in a 30+ point fantasy day. Oh, and the Pats will earn their third win of the season.

Maurice Jones-Drew NFL.com Analyst

Tough sledding for     Jalen Hurts     and     Bo Nix

See Full Page