Pubs, clubs and music venues in Australia's cocaine consumption capital will be able to keep medication on hand to reverse opioid overdoses.

Licensed venues in NSW have been invited to participate in a voluntary program providing naloxone nasal spray to keep in their first aid kits.

Additional training and expert advice will also be available to participating venues.

The nasal spray temporarily reverses opioid overdoses by blocking receptors in the brain, buying time to access treatment.

It has no effect on people who have not used opioids.

"Having this tool to help prevent deaths from overdoses brings NSW up to speed with leading international jurisdictions," the state's Night-Time Economy Minister John Graham said.

"Our venue operators care about safety and we're supporting them wi

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