The Buffalo Bills will aim to go 5-0 on the season when they host the New England Patriots on 'Sunday Night Football' in NFL Week 5. Josh Allen and the Bills are one of two undefeated teams remaining, while the division rival Patriots sit second in the AFC East standings at 2-2. Buffalo defeated the New Orleans Saints 31-19 in Week 4, while Drake Maye and the Patriots upended the Carolina Panthers 42-13.

Kickoff from Highmark Stadium is set for 8:20 p.m. ET. Buffalo is a 8.5-point favorite in the latest Patriots vs. Bills odds, and the over/under for total points scored is 49.5. The Bills are -424 favorites on the money line (risk $424 to win $100), while the Patriots are +328 underdogs (risk $100 to win $328). Before making any Bills vs. Patriots picks, be sure to see what the Spor

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