Chennai: The Ministry of Health and Family Welfare has confirmed that Coldrif Cough Syrup, manufactured by Sresan Pharma at its Kanchipuram, Tamil Nadu facility, contains diethylene glycol (DEG) beyond permissible limits. Fresh laboratory analysis has declared the drug Not of Standard Quality (NSQ), detecting a toxic 48.6% concentration of DEG, a substance linked to the deaths of at least nine children in Madhya Pradesh's Chhindwara district and two children in Rajasthan.
Diethylene glycol (DEG) is an organic compound found in household products but also as a counterfeit solvent in medicines. DEG poisonings are characterized by acute kidney injury (AKI).Diethylene glycol (DEG) is nephrotoxic, potentially resulting in high morbidity and mortality. Its main nephrotoxic by-product is diglyc