The Las Vegas Raiders (1-3) and Indianapolis Colts (3-1) clash Sunday in Week 5. Kickoff from Lucas Oil Stadium in Indianapolis is set for 1 p.m. ET (FOX). Let's analyze BetMGM Sportsbook's NFL odds around the Raiders vs. Colts odds and make our expert NFL picks and predictions for the best bets.

The Raiders have lost 3 straight after a season-opening win at the New England Patriots. They are coming off a 25-24 loss as a 1.5-point home favorite against the Chicago Bears in Week 4 as the Over (48) cashed. RB Ashton Jeanty recorded his first career 3-touchdown game, rushing for 138 yards and a score while adding 17 receiving yards and catching 2 touchdown passes. Las Vegas is 1-3 against the spread (ATS).

The Colts lost 27-20 at the LA Rams in Week 4, their first defeat of

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