A six-year-old girl is in a critical condition following a devastating crash in Virginia, north of Adelaide, on Sunday.

Emergency crews rushed to the scene just after 11am, where a Toyota van and a Toyota ute collided at the intersection of King Rd and Penfield Rd.

The young girl, a passenger in the van, was rushed to hospital with life-threatening injuries.

Two other children in the van, aged 10 and 11, along with the 42-year-old female driver from Murray Bridge, were also hospitalised with minor injuries.

The ute’s occupants — a 37-year-old Virginia man and a four-year-old girl — were taken to hospital with non-life-threatening injuries.

The intersection remains closed in all directions as police and Major Crash investigators comb the scene for clues.

Police are urging motorists to

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