The Buffalo Bills can't lock up an AFC East title quite yet, but they can go a long way in taking command of it when they meet the New England Patriots on 'Sunday Night Football' to highlight Week 5 of the NFL schedule. The Bills look to move to 5-0 on the season and, if they do, can grab a three-game lead within the division. Buffalo is an 8.5-point favorite over the Patriots (2-2). In other games involving AFC East foes, the Dolphins (1-3) are 1.5-point favorites against the Panthers (1-3) as Miami will play the rest of its season without Tyreek Hill. Meanwhile, the Jets (0-4) are 2.5-point underdogs against the visiting Cowboys (1-2-1), who will be without CeeDee Lamb (ankle), in the latest Week 5 NFL odds.

How should you handle those NFL games and optimize what to bet on NFL in Week 5

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