Marc Levy Takeda is preparing to take most of a 630,000-square-foot building in Cambridge’s Kendall Square next year for research and development.

Universities will suffer much more than industry from president Donald Trump’s radical change to H-1B visa processes, a local expert predicts.

A Sept. 19 executive order from Trump requires a $100,000 payment on new petitions submitted for H-1B visas , which let skilled foreign workers take jobs in the United States for up to six years. It was enacted almost immediately. Top sponsors in the area include biotechnology companies including Akamai, Moderna, Biogen, Takeda, as well as area academic institutions such as Harvard and MIT.

This year alone, 285 employers in Somerville and Cambridge sponsored almost 2,000 beneficiaries of the worke

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